Late 16th century; earliest use found in John Knox (c1514–1572), religious reformer. From post-classical Latin persecutrix female persecutor, feminine form corresponding to persecutor: see -trix.
Definition of persecutrix in US English:
persecutrix
nounˈpəːsɪkjuːtrɪks
A female persecutor.
Origin
Late 16th century; earliest use found in John Knox (c1514–1572), religious reformer. From post-classical Latin persecutrix female persecutor, feminine form corresponding to persecutor: see -trix.