A mutation caused by the addition or deletion of a base pair or base pairs in the DNA of a gene resulting in the translation of the genetic code in an unnatural reading frame from the position of the mutation to the end of the gene.
〔遗传〕移码突变
Example sentencesExamples
This frameshift mutation (deletion at positions 1151-1160) could be merely drifting to high frequency due to weak functional constraint.
We estimate that reversion of the lac mutation is about one-tenth as likely as a null frameshift mutation in a typical gene.
Thus, the base deletion that causes the frameshift mutation is present in the RNA population that was amplified as well as in the genomic DNA.
In ORF 2 there is a deletion of 11 nucleotides that causes a frameshift mutation and a premature stop codon; an additional 1 bp insertion is located further downstream.
The 25-bp insertion causes a frameshift mutation and creates stop codons in all three reading frames.