A heterocyclic compound which inhibits the growth of microtubules and which is used experimentally as an antineoplastic agent; methyl 5-(2-thenoyl)-2-benzimidazolecarbamate, C₁₄H₁₁N₃O₃S.
Origin
1970s; earliest use found in Journal of the American Medical Association. Probably from a rearrangement of onco- + -dazole.
Definition of nocodazole in US English:
nocodazole
nounnəʊˈkəʊdəzəʊl
Pharmacology
A heterocyclic compound which inhibits the growth of microtubules and which is used experimentally as an antineoplastic agent; methyl 5-(2-thenoyl)-2-benzimidazolecarbamate, C₁₄H₁₁N₃O₃S.
Origin
1970s; earliest use found in Journal of the American Medical Association. Probably from a rearrangement of onco- + -dazole.