Definition of leukaemogenic in English:
leukaemogenic
(US leukemogenic)
adjective luːˌkiːmə(ʊ)ˈdʒɛnɪklo͞oˌkēməˈjenik
Medicine Relating to or promoting the development of leukaemia.
〔医〕与白血病有关的；致白血病的
Example sentencesExamples
- As described earlier, protein dimerizations complicate the leukemogenic mechanism.
- However, caution must be exercised in making such assumptions because many inappropriately expressed genes from the leukemic clone may retain important diagnostic value, but prove not to be leukemogenic.
- The most widely accepted and significant leukemogenic mechanism attributed to the fusion protein involves the constitutive stimulation of tyrosine kinase.
- Hydroxycarbamide is the mainstay of treatment, but fears that it might be leukaemogenic led researchers to test other treatments including the antiplatelet drug anagrelide.
- This phenomenon can best be explained by the discovery that the site of breakage on chromosome 9 occurs at different places, which alters the product of the translocation and thus the leukemogenic mechanism.
Derivatives
nounluːˈkiːmədzən
Medicine Benzene is a human leukemogen and the metabolites are thought to be deeply involved in benzene leukemogenesis.
noun
Medicine These results will provide a better insight into understanding which metabolite is important in benzene leukemogenesis.
Example sentencesExamples
- This was most intense when he was working on his idea that there is no threshold for radiation-induced leukemogenesis.
- However, despite half a century of investigations, the mechanism of leukaemogenesis by benzene has not been fully elucidated and low dose effects cannot presently be estimated with confidence.
- We speculate that p53 protein overexpression in this bone marrow failure syndrome may represent an early indicator of significant DNA genetic alteration, which is a crucial step in the process of leukemogenesis.
- Our understanding of the molecular biology of the t translocation has contributed to the current theories of leukemogenesis in CML.