| 释义 |
Definition of cofactor in English: cofactornounˈkəʊfaktəˈkōˌfaktər 1A contributory cause of a disease. 致病原因 Example sentencesExamples - Gender, age and body mass index were taken into consideration as cofactors or covariates.
- Other cofactors include smoking, oral contraceptive use, multiparity, and possibly inflammation.
- One potentially important cofactor is human immunodeficiency virus type 1.
- Magnesium is an important cofactor in many enzymatic reactions.
- Anorectal infections are a potent cofactor for HIV transmission.
- Although numerous epidemiological studies have examined the association between risk of cervical cancer and dietary cofactors, most studies appear to have methodological limitations.
- The anaesthetics bind in a hydrophobic pocket which is the normal binding site for a necessary cofactor.
- Drugs and alcohol were a notable cofactor: 58 percent of the subjects reported being intoxicated during their last unprotected incident.
- To negate the effect of proximity to the microchip plant as a cofactor, the author compared clients and nonclients in the 3 zones of the exposure area.
- The causes are clearly different from risk factors, which are the diseases accompanying cofactors.
- Other cofactors also deserve vigorous investigation.
- Because many persons have these genotypes and only a few develop gluten-sensitive enteropathy, investigators have hypothesized that other genes or cofactors may be involved.
- Counseling can be offered to all patients with HCV infection to modify or prevent the adverse effects of cofactors, such as alcohol consumption, on disease progression.
- By getting the iron out of the liver and dealing with the other cofactors, a lot of people are going to lead normal, healthy lives without any problems.
- The other cofactors we considered are the other three families of drugs, the driver's age and sex, the type of vehicle driven, and the time of crash.
- Although population studies have shown no association between autism and MMR vaccine it has been further postulated that various environmental or genetic cofactors are required for the effect
- Alcohol intake is a cofactor in the rate of progression of chronic HCV infection.
- Cofactors are usually selected on the basis of simple forward selection, with markers entering the model individually rather than in pairs.
- The reasons are unknown but may be at least partially related to some environmental or genetic cofactors present that are necessary to trigger development of the disease.
- Any effect of breast feeding may be limited to a critical period or depend on other cofactors.
2Biochemistry
A substance (other than the substrate) whose presence is essential for the activity of an enzyme. 〔生化〕辅因子 Example sentencesExamples - Vitamin B 6 functions as a cofactor of many diverse enzymes in amino acid metabolism.
- Copper is usually utilized in organisms as a cofactor in enzymes or electron transfer proteins that catalyze redox reactions or oxygen chemistry.
- The most effective chemoprevention protocols would include antioxidants, other vitamins, minerals used as cofactors in antioxidant enzymes, and DNA protecting nutrients.
- Thiamine pyrophosphate, the active form of vitamin B-1, is a key cofactor of the essential enzymes involved in carbon metabolism.
- Modifications of proteins that depend upon vitamin C as a cofactor include proline and lysine hydroxylations.
3Mathematics
The quantity obtained from a determinant or a square matrix by removal of the row and column containing a specified element. 〔数〕余因子 Example sentencesExamples - Now, if A belongs to M n, then its matrix of cofactors A’ also has integer entries.
Definition of cofactor in US English: cofactornounˈkōˌfaktər 1A contributory cause of a disease. 致病原因 Example sentencesExamples - Other cofactors include smoking, oral contraceptive use, multiparity, and possibly inflammation.
- Other cofactors also deserve vigorous investigation.
- The anaesthetics bind in a hydrophobic pocket which is the normal binding site for a necessary cofactor.
- The causes are clearly different from risk factors, which are the diseases accompanying cofactors.
- Any effect of breast feeding may be limited to a critical period or depend on other cofactors.
- The other cofactors we considered are the other three families of drugs, the driver's age and sex, the type of vehicle driven, and the time of crash.
- Although numerous epidemiological studies have examined the association between risk of cervical cancer and dietary cofactors, most studies appear to have methodological limitations.
- Although population studies have shown no association between autism and MMR vaccine it has been further postulated that various environmental or genetic cofactors are required for the effect
- Counseling can be offered to all patients with HCV infection to modify or prevent the adverse effects of cofactors, such as alcohol consumption, on disease progression.
- Drugs and alcohol were a notable cofactor: 58 percent of the subjects reported being intoxicated during their last unprotected incident.
- One potentially important cofactor is human immunodeficiency virus type 1.
- Gender, age and body mass index were taken into consideration as cofactors or covariates.
- Magnesium is an important cofactor in many enzymatic reactions.
- By getting the iron out of the liver and dealing with the other cofactors, a lot of people are going to lead normal, healthy lives without any problems.
- Cofactors are usually selected on the basis of simple forward selection, with markers entering the model individually rather than in pairs.
- To negate the effect of proximity to the microchip plant as a cofactor, the author compared clients and nonclients in the 3 zones of the exposure area.
- The reasons are unknown but may be at least partially related to some environmental or genetic cofactors present that are necessary to trigger development of the disease.
- Alcohol intake is a cofactor in the rate of progression of chronic HCV infection.
- Because many persons have these genotypes and only a few develop gluten-sensitive enteropathy, investigators have hypothesized that other genes or cofactors may be involved.
- Anorectal infections are a potent cofactor for HIV transmission.
2Biochemistry
A substance (other than the substrate) whose presence is essential for the activity of an enzyme. 〔生化〕辅因子 Example sentencesExamples - Vitamin B 6 functions as a cofactor of many diverse enzymes in amino acid metabolism.
- Thiamine pyrophosphate, the active form of vitamin B-1, is a key cofactor of the essential enzymes involved in carbon metabolism.
- The most effective chemoprevention protocols would include antioxidants, other vitamins, minerals used as cofactors in antioxidant enzymes, and DNA protecting nutrients.
- Modifications of proteins that depend upon vitamin C as a cofactor include proline and lysine hydroxylations.
- Copper is usually utilized in organisms as a cofactor in enzymes or electron transfer proteins that catalyze redox reactions or oxygen chemistry.
3Mathematics
The quantity obtained from a determinant or a square matrix by removal of the row and column containing a specified element. 〔数〕余因子 Example sentencesExamples - Now, if A belongs to M n, then its matrix of cofactors A’ also has integer entries.
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