Late 18th century; earliest use found in George Huddesford (bap. 1749, d. 1809), satiric poet. From un- + pill + -ed. With the use in quot. 1973 compare pilled.
Definition of unpilled in US English:
unpilled
adjective(ˌ)ʌnˈpɪld
rare
Not treated with pills; unmedicated.
Origin
Late 18th century; earliest use found in George Huddesford (bap. 1749, d. 1809), satiric poet. From un- + pill + -ed. With the use in quot. 1973 compare pilled.