Definition of circularize in English:
 circularize
(British circularise)
verb ˈsəːkjʊlərʌɪzˈsərkjələˌraɪz
[with object]1Distribute a large number of letters or leaflets to (a group of people) in order to advertise something or canvas opinion.
给(一群人)发放大量信函(或传单、问卷)(做广告或征询意见)
 they circularize prospective purchasers at regular intervals
Example sentencesExamples
-  A questionnaire will be circularised shortly to help with the planning of a think tank.
 -  Some customers locally have been given notice of the impending closure, but not all houses appear to have been circularised as yet.
 -  The following morning Costello circularised clubs seeking nominations for the post.
 -  In January 1999, the general secretary circularised regions stating that the campaign was in breach of rules.
 -  They only realised the full implications of the story when they were forwarded the e-mail that had been circularised to the national media.
 -  At the same time he persuaded the Committee to circularize popular societies warning them not to fan superstition and fanaticism by persecution.
 -  In the event, only a few of these reports were completed and circularized to the committee.
 -  Companies, firms, businesses and individuals have been circularised and may contact any of the following regarding sponsorship and/or entries.
 -  The dissenters circularized all shareholders the following week to warn them about the new resolution.
 -  We have circularised here a proposal to allow the prime minister a one-and-a-half day week.
 -  This is a document which we sent to the Court after the draft was circularised.
 -  Shareholders in the company were thereafter circularised with the proposals.
 -  He communicated with shareholders, both by circularizing them and by his detailed interventions at shareholders' meetings.
 -  The factors highlighted in this paper which influence local inflation will be fully circularised over the next few months.
 
2Biochemistry 
Make (a stretch of DNA) into a circular loop.
〔生化〕将(一段DNA)弄成环状
Example sentencesExamples
-  Because intact lambda DNA has cohesive ends that can circularize, samples were heated to 65°C for 5 min and then cooled in ice to eliminate this possibility.
 -  Upon injection into the cell, the cohesive ends anneal and are ligated, circularizing the chromosome.
 -  The digested DNA was circularized by self-ligation.
 -  The plasmid DNA was then circularized with ligase and used to transform E. coli.
 -  Genomic DNA was digested with HindIII and circularized by ligation.
 
Derivatives
nounsəːkjʊlərʌɪˈzeɪʃ(ə)n
 Direct evidence for RNA circularization is shown in this illustration.
Example sentencesExamples
-  It was previously agreed that this will be dealt with by way of circularisation and a postal resolution.
 -  Ira provided a very convincing argument that, after infection, late gene expression must require circularization of the injected DNA.
 -  A large pool of DNA sequences was investigated by different authors, and their propensity to circularization was experimentally determined and predicted by theoretical approaches.
 -  Most Group I introns then simply catalyze their own circularization.
 
   Definition of circularize in US English:
 circularize
(British circularise)
verbˈsərkyələˌrīzˈsərkjələˌraɪz
[with object]1Distribute a large number of letters, leaflets, or questionnaires to (a group of people) in order to advertise something or canvas opinion.
给(一群人)发放大量信函(或传单、问卷)(做广告或征询意见)
 they circularize prospective purchasers at regular intervals
Example sentencesExamples
-  In January 1999, the general secretary circularised regions stating that the campaign was in breach of rules.
 -  Companies, firms, businesses and individuals have been circularised and may contact any of the following regarding sponsorship and/or entries.
 -  In the event, only a few of these reports were completed and circularized to the committee.
 -  Shareholders in the company were thereafter circularised with the proposals.
 -  We have circularised here a proposal to allow the prime minister a one-and-a-half day week.
 -  The factors highlighted in this paper which influence local inflation will be fully circularised over the next few months.
 -  They only realised the full implications of the story when they were forwarded the e-mail that had been circularised to the national media.
 -  A questionnaire will be circularised shortly to help with the planning of a think tank.
 -  This is a document which we sent to the Court after the draft was circularised.
 -  Some customers locally have been given notice of the impending closure, but not all houses appear to have been circularised as yet.
 -  At the same time he persuaded the Committee to circularize popular societies warning them not to fan superstition and fanaticism by persecution.
 -  The following morning Costello circularised clubs seeking nominations for the post.
 -  The dissenters circularized all shareholders the following week to warn them about the new resolution.
 -  He communicated with shareholders, both by circularizing them and by his detailed interventions at shareholders' meetings.
 
2Biochemistry 
Make (a stretch of DNA) into a circular loop.
〔生化〕将(一段DNA)弄成环状
Example sentencesExamples
-  Genomic DNA was digested with HindIII and circularized by ligation.
 -  The digested DNA was circularized by self-ligation.
 -  The plasmid DNA was then circularized with ligase and used to transform E. coli.
 -  Because intact lambda DNA has cohesive ends that can circularize, samples were heated to 65°C for 5 min and then cooled in ice to eliminate this possibility.
 -  Upon injection into the cell, the cohesive ends anneal and are ligated, circularizing the chromosome.