A mutation affecting only one or very few nucleotides in a gene sequence.
〔遗传〕基因点突变
Example sentencesExamples
Each mutant allele contains a point mutation, and the positions of the Kitl sequences affected in each are shown in Table 1.
Arrows indicate the position of the point mutation and the corresponding nucleotide on the wild-type sequence (right).
To introduce a point mutation the gene must be cloned, the desired point mutation must be generated within that clone, and an I-SceI site must be inserted.
If one of the alleles carries a recessive mutation, such as a point mutation, a second event that creates LOH could be any genetic alteration that inactivates the remaining allele.
So tell me how a simple point mutation changes the information content of the gene.
Definition of point mutation in US English:
point mutation
noun
Genetics
A mutation affecting only one or very few nucleotides in a gene sequence.
〔遗传〕基因点突变
Example sentencesExamples
So tell me how a simple point mutation changes the information content of the gene.
If one of the alleles carries a recessive mutation, such as a point mutation, a second event that creates LOH could be any genetic alteration that inactivates the remaining allele.
To introduce a point mutation the gene must be cloned, the desired point mutation must be generated within that clone, and an I-SceI site must be inserted.
Each mutant allele contains a point mutation, and the positions of the Kitl sequences affected in each are shown in Table 1.
Arrows indicate the position of the point mutation and the corresponding nucleotide on the wild-type sequence (right).